Anti-biofilm effectiveness of protocols for cleaning complete dentures in hospitalized patients: a randomized controlled trial

Abstract Denture biofilm acts as a potential reservoir for respiratory pathogens, considerably increasing the risk of lung infections, specifically aspiration pneumonia, mainly 48h after hospital admission. The establishment of a straightforward, affordable, and applicable hygiene protocol in a hospital environment for the effective control of denture biofilm can be particularly useful to prevent respiratory infections or reduce the course of established lung disease. Objectives To evaluate the anti-biofilm effectiveness of denture cleaning protocols in hospitalized patients. Methodology The maxillary complete dentures (MCDs) of 340 hospitalized participants were randomly cleaned once using one of the following 17 protocols (n=20): brushing with distilled water, toothpaste, or neutral liquid soap (controls); immersion in chemical solutions (1% sodium hypochlorite, alkaline peroxide, 0.12% or 2% chlorhexidine digluconate), or microwave irradiation (650 W for 3 min) combined or not with brushing. Before and after the application of the protocols, the biofilm of the intaglio surface of the MCDs was evaluated using two methods: denture biofilm coverage area (%) and microbiological quantitative cultures on blood agar and Sabouraud Dextrose Agar (CFU/mL). Data were subjected to the Wilcoxon and Kruskal-Wallis tests (α=0.05). Results All 17 protocols significantly reduced the percentage area of denture biofilm and microbial and fungal load (P<0.05). The highest percentage reductions in the area of denture biofilm were observed for 1% hypochlorite solution with or without brushing and for 2% chlorhexidine solution and microwave irradiation only in association with brushing (P<0.05). The greatest reductions in microbial and fungal load were found for the groups that used solutions of 2% chlorhexidine and 1% hypochlorite and microwave irradiation, regardless of the association with brushing (P<0.05). Conclusions A single immersion for 10 min in 1% sodium hypochlorite, even in the absence of brushing, proved to be a straightforward, rapid, low-cost, and effective protocol for cleaning the dentures of hospitalized patients.

Eficácia das técnicas de higiene oral em pacientes internados em unidades de terapia intensiva / Effectiveness of oral hygiene techniques in patients hospitalized in intensive care units

Objetivo: verificar a eficácia das técnicas de higiene oral, solução de clorexidina com gaze e espátula e da escovação dentária com solução de clorexidina no controle microbiológico oral de pacientes internados em UTI. Metodologia: as bases de dados utilizadas foram PUB MED, MEDLINE, SCIELO e LILACS em março a julho de 2019. Foram incluídos artigos na língua inglesa e portuguesa, disponíveis em livre acesso com o texto completo, com período de publicação entre 2009 a 2019 e que abordassem sobre os métodos de higiene oral na UTI e relacionasse a enfermidades encontradas nesse ambiente. Resultados: foram encontrados 32 artigos, 8 se enquadravam nos critérios de inclusão. Os artigos de revisão evidenciaram a importância da higiene oral em pacientes com ventilação mecânica e relatam o uso da clorexidina como método eficaz na prevenção de PAV. Já nos estudos clínicos randomizados, mostram não haver diferença estatisticamente significativa entre o uso da escova dental e a solução de clorexidina 0,12%. Conclusão: ambos os métodos são eficientes na higienização oral de pacientes internados e que não há diferença significativa nos estudos quando comparam a escova de dentes com o uso da clorexidina com gaze para a higiene oral na UTI. Mas quando se fala em prevenção de PAV, a clorexidina 0,12% é o mais citado(AU)

Objective: to verify the effectiveness of oral hygiene techniques, chlorhexidine solution with gauze and spatula and toothbrushing with chlorhexidine solution in the oral microbiological control of patients admitted to the ICU. Methodology: the databases used were PUB MED, MEDLINE, SCIELO and LILACS in March to July 2019. Articles in English and Portuguese were included, freely available with the full text, with a period of publication between 2009 and 2019 and to address oral hygiene methods in the ICU and relate to diseases found in that environment. Results: 32 articles were found, 8 fit the inclusion criteria. The review articles highlighted the importance of oral hygiene in patients with mechanical ventilation and report the use of chlorhexidine as an effective method in preventing VAP. In randomized clinical studies, however, they show no statistically significant difference between the use of the toothbrush and the 0.12% chlorhexidine solution. Conclusion: both methods are efficient in oral hygiene of hospitalized patients and that there is no significant difference in the studies when comparing the toothbrush with the use of chlorhexidine with gauze for oral hygiene in the ICU. But when talking about VAP prevention, 0.12% chlorhexidine is the most cited(AU)

Considerações sobre os tipos de próteses parciais removíveis e seu impacto na qualidade de vida / Considerations on types of removable partial dentures and their impact on oral health

O objetivo deste estudo foi discutir, por meio de uma revisão de literatura, as indicações, contraindicações, vantagens, desvantagens das alternativas reabilitadoras mais comuns utilizando PPRs e o impacto desses tratamentos na qualidade de vida relacionada à saúde bucal dos pacientes. Foi realizada uma pesquisa ampla na literatura, com a utilização dos termos "Prótese Parcial Removível", "Qualidade de Vida", "Saúde bucal"; "Satisfação do Paciente", no período entre 1990 e 2018, no Medline, Google Scholar, internet e livros didáticos. Foi demonstrado que a reabilitação com PPRs associadas a implantes resultou em melhor qualidade de vida associada à saúde bucal dos usuários, seguida por PPRs retidas por encaixe e PPRs convencionais. Entretanto, o profissional deve considerar as condições sistêmicas, bucais e econômicas de cada paciente, tendo o conhecimento biomecânico bem como a ciência dos benefícios e das desvantagens de cada tipo de tratamento para estabelecer um correto diagnóstico do caso e, assim, indicar o melhor tipo de PPR. Dessa forma, é possível oferecer o melhor tratamento para cada paciente parcialmente edêntulo, devolvendo estética e função de maneira satisfatória de modo a resultar em maior nível de satisfação e qualidade de vida(AU)

The purpose of this study was to discuss, through a review of the literature, indications, contraindications, advantages, disadvantages of the most common rehabilitation alternatives using RPDs and the impact of these treatments on patients' oral health quality of life. A broad research was conducted in the literature, using the terms "Partial Removable Prosthesis", "Quality of Life", "Oral Health"; "Patient Satisfaction" in the period between 1990 and 2018, in Medline, Google Scholar, internet and textbooks. It was demonstrated that rehabilitation with RPDs associated with implants resulted in a better oral health quality of life of users, followed by RPDs with attachments and conventional RPDs. However, the professional should consider the systemic, oral and economic conditions of each patient, based on the biomechanical knowledge, as well as the science of the benefits and disadvantages of each type of treatment to establish a correct diagnosis of the case, and thus, indicate the best type of RPD. In this way, it is possible to offer the best treatment for each partially edentulous patient, returning aesthetics and function in a satisfactory manner in order to result in a higher level of satisfaction and quality of life(AU)